EU-JordanNet II Projects with Jordanian partners that finished between 31/12/2011 and 31/05/2015
JEWEL - Jordan Europe Wide Enhanced research Links in ICT

JoRiew - Improving Capacity of Jordanian Research in Integrated Renewable Energy and Water Supply

WASSERMed - Water Availability and Security in Southern Europe and the Mediterranean

KHCBIO - Supporting the Establishment of a Cancer Biobank for Jordan and its Neighbouring Countries Through Knowledge Transfer & Training

RESSOL-MEDBUILD - RESearch Elevation on Integration of SOLar Technologies into MEDiterranean BUILDings

MIRA - Mediterranean Innovation and Research Cooperation Action

IJERA - Integrating Jordan into the European Research Area

JOCHERA - Jordan Conservation of Cultural Heritage in ERA

EU-JORDANNET

BioWALK 4 Biofuels

BOT-ERA “Reinforcing cooperation between the Royal Botanic Garden of Jordan and ERA (BOT-ERA)”

J-ERA Center

LINKSCEEM-2: Linking Scientific Computing in Europe and the Eastern Mediterranean – Phase 2

"Euro-Mediterranean research cooperation on gender and science: SHE Euro-Mediterranean Research Area” (SHEMERA)

Project name: KHCBIO - Supporting the Establishment of a Cancer Biobank for Jordan and its Neighbouring Countries Through Knowledge Transfer & Training

Thematic area: Health [INCO.2011-6.2]

BRIEF SUMMARY OF OVERALL PROJECT WITH THE MAIN OBJECTIVES

King Hussein Cancer Center (KHCC) is a highly accredited hospital that treats over 3,500 new adult and paediatric cancer patients annually from Jordan and its neighbouring countries. KHCC wishes to maintain its pioneering position in cancer detection and treatment and plans to establish a state-of-the-art bio specimen repository (KHCCBIO) to store and archive biospecimens for use in cancer research with the support and experience of experts in biobanking and quality management from Trinity College Dublin and two European SMEs. Because many of the biospecimens in collections around the world are not suitable for making the type of direct comparisons that modern cancer biology research demands due to poor quality and preservation techniques used to prepare them, KHCCBIO bank will help change all that by providing a bank of biospecimens, from a diverse ethnic Middle Eastern population that will be a valuable resource in our arsenal in the battle against cancer. KHCCBIO will collect, process, and store high-quality, clinically annotated bio specimens from consented patients and distribute them to researchers worldwide. It is being established using current international guidelines and will incorporate the highest level of Quality Management System based on ISO standards. European partners will deliver training and support to KHCCBIO employees and provide a proven solution, based on existing licensed technology.

THE PROBLEM AREA ADDRESSED

In the post-genomics era of biomedical science, bio specimens are assuming an even more prominent role in efforts to identify the key genes, RNAs, proteins, and signalling networks involved in cancer and then use that information to detect cancer at its earliest stages and develop a personalised therapeutic regimen to treat it. Indeed, the very future of personalised medicine depends on the ability of researchers to compare the molecular workings from hundreds of bio specimens and tease out the differences that have diagnostic and therapeutic value. Unfortunately, the vast majority of the millions of bio specimens currently in collections around the world are not suitable for making the type of direct comparisons that modern cancer biology research demands. The reason is simple: no standard protocol has governed how surgeons collect tissue samples, how pathologists prepare those specimens, and how tissue banks store their collected biospecimens. And, given the exquisite sensitivity of today's analytical techniques, it is nearly impossible to distinguish between molecular fingerprints related to cancer and results arising from the way a given biospecimen was handled. Hence, KHCCBIO is being established for the purpose of collecting, processing, storing and distributing high-quality, clinically annotated biospecimens from consented patients using current international guidelines implementing the highest level of Quality Management System based on ISO standards.

DESCRIPTION OF THE ACHIEVEMENTS

Training:
Training for the medical technologists, document controller and pathologist was held at TCD and Biostor in Ireland.
A four day-workshop was held during the annual meeting to discuss the progress in the joint project and develop plans to assure the growth and stability of the first biobank in the area. The partners discussed deliverables, policies and procedures, equipment and upcoming activities of the project. Furthermore, hands-on training for KHCCBIO tissue-bank staff was held in house to assure the quality and validation of the procedures supervised by TCD and Biostor.
Deliverables fulfilled so far.
  • KHCCBIO Quality Policy Manual and Validation Plan were prepared.
  • Consent policy, consent IPPs and forms and data privacy policy were written and approved.
  • Installation Qualification Protocol for the Equipment/System was established.
  • Dissemination and exploitation plan was written and implemented.
  • Public website was launched in 2012.
  • Several press release and radio and TV interviews were conducted to promote the project and to increase public awareness.
  • Project related brochures were written and distributed.
  • Governance & Research Ethics Committee established.
  • Database of contacts, organisations, local/regional/national/pan-European authorities established.
  • Polices for Thoracic tissue & associated blood sample procurement, processing and preservation were written.
  • Taking a part in targeted events such as meetings and conferences to promote KHCCBIO bank.

PUBLICATIONS AND OTHER AVAILABLE DOCUMENTATION

A. Posters, conferences and oral presentations
1. November 7-10, 2012- ESBB annual meeting 2012 in Granada. ESBB and Spanish national biobank network joint conference. Oral presentation: Dr. Maher Sughayer, "The progressive challenges approaches at the bio banking in emerging countries".
2. October 22-23, 2012 - International Conference on Mediterranean Countries and EU Opportunities. Le M‚ridien Hotel, Amman. Jordan.
> Oral presentation: Dr. Maher Sughayer. Session 2: Synergies, Complementarities and Networking. KHCCBIO Era-wide project. Jordan.
> Poster presentation: KHCCBIO - Supporting the Establishment of a Cancer Biobank for Jordan and its Neighboring Countries Through Knowledge Transfer & Training. Mohammad Mustafa, B.Sc., Lina Souan, M.Sc., Ph.D., Khetam Hamza, M.Sc., Maxim Al-Ashhab, MD., and Maher Sughayer, MD.
3. March 23-26, 2013 - 3rd International Jordanian Medical Laboratories Conference. Landmark hotel. Amman, Jordan. Oral presentation: Dr. Maher Sughayer, "Tissue banking".
4. April 16, 2013 - Jordan Europe Wide Enhanced research Links in ICT (JEWEL) conference "Get ready for HORIZON 2020". Landmark hotel, Amman, Jordan. Poster presentation. KHCCBIO - Supporting the Establishment of a Cancer Biobank for Jordan and its Neighbouring Countries Through Knowledge Transfer & Training. Lina Souan, M.Sc., Ph.D., Mohammad Mustafa, B.Sc. , Khetam Hamza, M.Sc., Sallam Al Hassoon, M.Sc., Maxim Al-Ashhab, MD, PhD, and Maher Sughayer, MD.
5. April 19-27, 2013 - Arab Medical Association Against Cancer (AMAAC). The 13th Pan Arab Cancer Congress. Le Meridien Hotel, Amman, Jordan. Poster presentation. KHCCBIO - Supporting the Establishment of a Cancer Biobank for Jordan and its Neighbouring Countries Through Knowledge Transfer & Training. Lina Souan, M.Sc., Ph.D., Mohammad Mustafa, B.Sc. , Khetam Hamza, M.Sc., Sallam Al Hassoon, M.Sc., Maxim Al-Ashhab, MD, PhD, and Maher Sughayer, MD.
B. Flyers:
1. KHCCBIO - Supporting the Establishment of a Cancer Biobank for Jordan and its Neighboring Countries Through Knowledge Transfer & Training
2. In collaboration with EU members through FP7 project, King Hussein Cancer Center is in the process of establishing the first ISO compliant Biobank in Jordan and the Region

C. Scientific Publication:
Rita T. Lawlor, Patrick M. Sluss, Rupert Langer, Maher A. Sughayer, Michael A. Igbe, Khalid Siddiqui, Pasquale De Blasio, Bonginkosi Duma, Maimuna Mendy, Christian Chabannon, and Muntaser Ibrahim. European, Middle Eastern, and African Society for Biopreservation and Biobanking (ESBB). 2012 Conference Session on Biobanking in Emerging Countries.
BIOPRESERVATION AND BIOBANKING. Volume 11, Number 3, 2013.
DOI: 10.1089/bio.2013.0017